The following alphabetical list provides the two letter label, the relevant alias, and at least one example for all searchable CANCERLIT fields:
|
===== |
============ Name/Example ============ |
|
| AB | Abstract bone density.ab. drug abuse.ab. |
|
|
CANCERLIT includes author-written abstracts from journals whose publisher gave NLM permission for their use. These abstracts appear in the Abstract (AB) field. Over 80% of the documents in CANCERLIT contain abstracts. Abstracts which exceed 250 words (or, for core cancer journals or long articles, 400 words) are truncated. The Abstract field includes a display of number of References in an article. |
||
| AF | All Searchable
Fields heart disease.af. liver.af. |
|
|
All Fields (AF) is an alias for all of the fields which occur in the source documents, including value-added fields such as Subject Headings. The only thing excluded from an All Fields search are fields such as "floating subheading" or "heading word" which are created by the loading process and do not actually appear in the record. |
||
| AU | Author ochsner jl.au. smith $.au. |
|
|
The Author (AU) field contains up to twenty-five authors. The format for authors is last name followed by one or more initials: Smith JC or Smith J. Enter the last name, or if it is a common name, enter the last name and first initial. If you are unsure of the spelling of the last name (macdonald or mcdonald), enter one version and then scroll through the list of names to find the other. |
||
| EM, UP, IM, ND, LR | Entry Month 20010604.em. 19870101.em. |
|
|
The Entry Month (EM) field contains the issue (year and month) in which a document appeared in Index Medicus or other source publications. The EM field appears in the format YYYYMMDD. If a revision to a document has occurred, the EM field will also contain the revision date. |
||
| FS | Floating Subheading et.fs. di.fs. |
|
|
Subheadings are qualifiers added to MeSH subject headings to refine their meaning. Terms such as "etiology" or "therapy", when combined with a MeSH heading, give a very precise idea of what an article covers. The Floating Subheading (FS) field contains the 2-letter codes, such as "po" for poisoning. The fully spelled out subheadings for any particular MeSH heading can be viewed using the pull-down menu TOOLS/Subheadings. |
||
| GS | Gene Symbol znf74.gs. |
|
|
The Gene Symbol (GS) field contains Gene Symbols as they are entered into the original document. The GS field sometimes conforms to standardized human gene nomenclature. Ignore super or sub-scripts in entry of a gene symbol. For example, psub 120 would be entered as p120. Beginning in 1996, data will no longer be added to this field. |
||
| GW | Gene Symbol Word | |
|
The Gene Word (GW) field contains individual words from the Gene Symbol field. This field does not display. |
||
| HW, ME | Subject Heading Word diazepam.hw. blood.hw. |
|
|
Sometimes you may wish to retrieve every MeSH subject heading that includes a particular word; this is done by searching the single word in the Subject Heading Word (HW) field. You can also view every MeSH Subject Heading which contains a particular word by using the pull-down menu TOOLS/Permuted Index. |
||
| IN | Institution harvard.in. case western.in. |
|
|
The Institution (IN) field contains the primary author's affiliation, which is usually the source for a reprint of the article. This information is available for most documents since 1988. Beginning with documents indexed in 1996, the primary author's email address will also be included, if present in the journal. The information is taken from the source document and is not standardized. Enter the single most descriptive word in an institution (harvard, not university). Consider both full spellings and abbreviations. |
||
| IP | Issue/Part "3".ip. "45".ip. |
|
|
The Issue/part field (IP) contains the Issue and/or part for a particular volume of a journal. The IP field usually displays as part of the Source (SO) field. |
||
| IS | ISSN Number 8756 7938.is. 0001 4001.is. |
|
|
The ISSN (IS) field contains the International Standard Serial Number (ISSN) for the journal in which an article was published. |
||
| JC | NLM Journal Code kfr.jc. dqf.jc. |
|
|
The Journal Code (JC) is an alpha-numeric code established by NLM which uniquely identifies every journal indexed in the NLM databases. |
||
| JN, JT | Journal Name archives of dermatology.jn. jama.jn. |
|
|
The Journal Name (JN) field contains the full name of the journal in which the article was published. Journal names are indexed as phrases, so enter enough letters of the journal name to locate the name in the index. Stopwords such as "of" ARE included in the JN index, but when "the" is the first word of a journal, it has been stripped. |
||
| JW | Journal Word obstetrics.jw. psychology.jw. |
|
|
The Journal Word (JW) field contains individual words from every journal name in CANCERLIT. Stopwords such as "the" or "of" are not included. This field is used to retrieve every occurrence of a journal which includes a particular word, such as "obstetrics". |
||
| LG, LA | Language fre.lg. eng.lg. |
|
|
The Language (LG) field contains the language(s) of publication of an article. The language name is spelled out and is also indicated by a 3-letter code (such as fre for French). You can enter either the 3-letter code or fully-spelled language. The language index is quickly scrollable to determine all languages which appear in CANCERLIT. |
||
| MS | Molecular Sequence genbank.ms. |
|
|
The Molecular Sequence (MS) field contains an organizational acronym and the unique identifier that organization has applied to a molecular sequence. The acronym appears first followed by a hyphen and the unique identifier, as in genbank-60485. The Molecular Sequence (MS) field was added to MEDLINE in 1988 and is new to CANCERLIT in 2001. |
||
| NO | Grant Number zo1 cd00036 01.no. |
|
|
The Grant Numbers (NO) field contains the Grant or contract number for articles or publications generated by support with US federal funds. Grant or contract numbers are displayed in full, but special characters except hyphens have been removed from the index. |
||
| PB | Publisher growth.pb. zhonghua.pb. |
|
|
The Publisher (PB) field contains publisher information for books, monographs or any non-journal publications. This information is taken from the source document as it appears, so variant forms of a publisher are possible. |
||
| PG | Page "44".pg. "237".pg. |
|
|
The Page (PG) field consists of the inclusive pagination of a journal article. This field is usually displayed as part of the Source (SO) field. |
||
| PM | PubMed Identifier 10608668.pm. |
|
|
The PubMed Identifier (PM) field contains the PubMed number first assigned by NLM. This number is another unique identifier of the records. |
||
| PN | Personal Name as Subject Heading lombard hl.pn. |
|
|
If an article is an interview, an obituary, or simply discusses a well-known person, that person's name will appear in the Personal Name As Subject (PN) field. The format for the Personal Name field is the same as that for the Author field—last name and initials, as in Haddow A. Enter a last name and one initial, if known. |
||
| PT | Publication Type bibliography.pt. review.pt. |
|
|
In addition to indexing documents with Medical Subject Headings, the indexers at the National Library of Medicine assign terms to describe the article type. These terms appear in the Publication Type (PT) field. |
||
| RN | CAS Registry Number zk 119010.rn. 0 001 c8 nbd.rn. |
|
|
The Registry Number (RN) field contains the Chemical Abstracts Service Registry number or Enzyme Commission number for a compound mentioned in an article. If the generic compound name can be determined, it is included. Hyphens are not used in the index although they do appear in the record display. Registry numbers appear with hyphens (50-07-0); EC numbers appear in the format ec 1-1-1-3; and chemical names appear with all special characters except hyphens removed. |
||
| RW | CAS Registry Number Word binding.rw. enzyme$.rw. |
|
|
The CAS Registry Word (RW) field contains single words from the registry number field and is used to search portions of chemical names. The Registry Number (RN) field was added to MEDLINE in 1980 and is new to CANCERLIT for 2001. |
||
| SB | Journal Subset d.sb. |
|
|
The Subset (SB) field in CANCERLIT is used to identify the source of the document. To eliminate overlap between MEDLINE and CANCERLIT, use the limit option or the command syntax: 4 not l.sb. |
||
| SH, DE, SW | MeSH Subject Heading ulcer.sh. sarcoma kaposi.sh. |
|
|
The MeSH Heading (SH) field contains the Medical Subject Headings used by indexers at the National Library of Medicine (NLM) to describe the content of an article. NLM's MeSH terms are organized in a hierarchy, or "tree" structure. You can look up any subject heading using the TOOLS/Tree pull-down menu. MeSH headings are entered into the index as phrases and should be searched as they appear in the NLM MeSH books or in our Tree display. |
||
| SO | Source (JN, JA, PB, PG, YR, VO, IP) baltimore.so. brain.so. |
|
|
The Source (SO) field includes a display of all the basic information needed to locate a citation, including the Journal Name or Monograph Publisher, the Vol/Issue, pagination and year of publication. |
||
| TI | Title bone.ti. nursing care.ti. |
|
|
The Title (TI) field contains the English language version of a title. For documents which were not written in English, the original or transliterated title appears in a separate field, Original Title (OT). Stopwords such as "of" or "the" will display in documents but do not appear in the Title index. However, the word "a", which is a stopword in other fields CAN be searched in titles. |
||
| TW | Text Word (AB, TI) diazepam.tw. squibb.tw. |
|
|
The Textword (TW) field is an alias for all of the fields in a database which contain text words and which are appropriate for a subject search. The Textword field in CANCERLIT includes Title (TI) and Abstract (AB). |
||
| UI, AN | Unique Identifier 83050448.ui. 99275725.ui. |
|
|
The Unique Identifier (UI) field contains an 8-digit number assigned by CANCERLIT to uniquely identify a particular record. This number is also the one used to locate the document through NLM's document delivery service. |
||
| VO | Volume "49".vo. "13".vo. |
|
|
The Volume (VO) field consists of the volume and issue of a serial publication. This field is usually displayed as part of the Source (SO) field. |
||
| XM | Exploded MeSH Heading "dopamine agents*".xm. exocrine glands.xm. |
|
|
MeSH Subject Headings are hierarchical, with up to twelve levels of narrower terms from the top of a hierarchy. In order to retrieve a term and all of its narrower terms, a subject headings must be "exploded", that is, the subject heading and all narrower terms are "OR'd" together. OVID pre-explodes highly-posted broader terms with their narrower terms during loading. These pre-exploded MeSH Headings appear in the XM field. |
||
| XS | Exploded Subheading ae.xs. di.xs. |
|
|
Sometimes multiple MeSH Subheadings can be logically grouped together. Such related groups of subheadings are "pre-exploded" under one broad subheading. This means that all the grouped subheadings can be retrieved together by searching on the "pre-exploded" version of the broad subheading. The 2-letter codes for the pre-exploded subheadings appear in the Exploded Subheading (XS) field. |
||
| YR | Year of Publication 1983.yr. 1996.yr. |
|
|
The Year (YR) field contains the year in which an article was published. |
||
Abstracts Command Syntax: ..l/ ab=y Sentence Syntax: limit 1 to abstracts Age Groups Sentence Syntax: limit 1 to infant limit 2 to adult Animal/Human Command Syntax: ..l/1 hu=y Sentence Syntax: limit 1 to human limit 1 to animal Animal Types Sentence Syntax: limit 1 to cats limit 1 to rabbits English Language Command Syntax: ..l/1 en=y Sentence Syntax: limit 1 to english Female/Male Sentence Syntax: limit 1 to female limit 1 to male Ovid Full Text Available Sentence Syntax: limit 1 to ovid full text available Languages Command Syntax: ..l/1 lg=fre Sentence Syntax: limit 1 to french Latest Update Sentence Syntax limit 1 to latest update Non-MEDLINE Sentence Syntax: limit 1 to nonmedline Publication Types Sentence Syntax: limit 1 to clinical trial limit 1 to review Publication Years Sentence Syntax: limit 1 to yr=1996
Online the only segment up for use is the Multi-segment Canc.
Coverage for Segments Local: 1999-present use canc or ..c/canc 1996-1998 use canc4 or ..c/canc4 1991-1995 use canc3 or ..c/canc3 1985-1990 use canc2 or ..c/canc2 1975-1984 use canc1 or ..c/canc1
Unique Identifier
81077285
PubMed Identifier
6160586
Authors
Attie AD. Pittman RC. Steinberg D.
Title
Metabolism of native and of lactosylated human low density lipoprotein:
evidence for two pathways for catabolism of exogenous proteins in rat hepatocytes.
Source
Proceedings of the National Academy of Sciences of the United States of
America. 77(10):5923-7, 1980 Oct.
NLM Journal Code
pv3, PV3, PV3, 7505876
Journal Subset
IM
Country of Publication
United States
MeSH Subject Headings
Animal
Cholesterol / me [Metabolism]
Colchicine / pd [Pharmacology]
*Glycoproteins / me [Metabolism]
Human
Hydroxymethylglutaryl CoA Reductases / me [Metabolism]
*Lactose / me [Metabolism]
*Lipoproteins, LDL / me [Metabolism]
*Liver / me [Metabolism]
Lysosomes / me [Metabolism]
Metabolic Clearance Rate
Rats
Support, U.S. Gov't, P.H.S.
alpha-Fetoproteins / me [Metabolism]
Abstract
Human low density lipoprotein (LDL) covalently conjugated with 200-250
residues of lactose per LDL particle (Lac-LDL) was bound and rapidly taken
up by the galactose-specific receptor of rat hepatocytes. Uptake of Lac-LDL
was associated with inhibition of droxy-3-methylglutaryl-CoA reductase
and stimulation of cholesterol esterification. Uptake of native human LDL
had no significant effects on these enzyme activities even when the rates
of LDL uptake equaled those of Lac-LDL. When injected into rats, Lac-LDL
was selectively removed by the liver (98% of injected dose). The hepatic
subcellular distribution of simultaneously injected native 125I-labeled
LDL and 131I-labeled Lac-LDL differed significantly, Lac-LDL was associated
with fractions enriched in lysosomal hydrolases whereas native LDL was
found predominantly in the supernatant fraction enriched in lactate dehydrogenase.
Chloroquine (0.1 mM) markedly suppressed uptake of Lac-LDL by cultured
rat hepatocytes (> 80%) but had only a small effect on uptake of native
LDL. Leupeptin (0.625 mM) inhibited degradation of Lac-LDL more than it
did degradation of native LDL. Colchicine (0.25 microM) dramatically suppressed
uptake of Lac-LDL (> 70%) but did not affect native LDL uptake even at
concentrations as high as 10 microM. Uptake of human LDL by rat hepatocytes
occurs largely by nonspecific mechanisms, including fluid endocytosis,
whereas Lac-LDL, as shown here, is taken up by a specific receptor-mediated
mechanism. The results show further that native human LDL, representing
an example of a protein taken up nonspecifically, is processed intracellularly
by a pathway qualitatively distinct from that for Lac-LDL, an example of
a protein taken up by a specific mechanism. Lac-LDL may serve as a vehicle
for specifically delivering drugs, hormones, or radioactive compounds to
hepatocytes for therapeutic or diagnostic purposes.
Registry Numbers
0 (Glycoproteins). 0 (Lipoproteins, LDL). 0 (alpha-Fetoproteins). 0 (lactosylated
LDL). 57-88-5 (Cholesterol). 63-42-3 (Lactose). 64-86-8 (Colchicine). EC
1-1-1-88 (Hydroxymethylglutaryl CoA Reductases).
ISSN
0027-8424
Publication Type
Journal Article.
Language
English
Grant Numbers
HL-07276 (NHLBI), HL-14197 (NHLBI)
Entry Month
19810226 Revised: 20001218. Entry Week: 19810226.
The NCI represents that CANCERLIT is formulated with a reasonable standard of care. Except for this representation, NCI makes no representations or warranties, express or implied, including any implied warranty of merchantability or fitness for a particular purpose, with respect to CANCERLIT. The documents contained in CANCERLIT may be retained for personal or educational use only. Information should not be edited or modified. Any resale or redistribution of all or portions of the information is not permitted.
Because use of the CANCERLIT database for insurance reimbursement decisions is contrary to the nature of the database, which is designed as a research tool and not to reflect all possible treatment options, customers agree to not make the database available to users who wish to use it for reimbursement decision purposes.
Revised 18 September 2001