The Physician Data Query Cancer file contains prognostic and treatment information for over 80 different cancers. Included is up-to-date information on prognosis, staging, cellular classification and treatment options, both standard and under clinical investigation, along with references to medical literature. An editorial board of prominent oncologists meets each month to review and update the information in PDQC.
PDQC contains over 80 documents, each devoted to a particular cancer type. See Additional Notes for a list of the cancer names currently included in PDQC. For clinical trial information, search the PDQP database; for closed clinical trial information search the PDQB database.
The following alphabetical list provides the two-letter label, the relevant alias, and an example for each PDQ Cancer Information File database field.
===== ============ Label Name/Example ===== ============ an Accession Number [Word and Phrase Indexed] example 1: PDQC-000006.an. example 2: 000006.an. ca Cancer Terminology Superlabel [CN, SY, CT fields] example: stomach cancer.ca. cc Cellular Classification [Word Indexed] example: ulcerating.cc. cn Cancer Name [Word Indexed] example: gastric cancer.cn. ct Cell Type/Stage [Word Indexed] example: recurrent gastric cancer.ct. pg Prognosis [Word Indexed] example: survival rate.pg. si Stage Information [Word Indexed] example: nodal involvement.si. ss Summary Statement [Word Indexed] example: advanced stage.ss. sy Synonyms [Word Indexed] example: stomach cancer.sy. to Treatment Overview [Word Indexed] example: combined modality.to. tp Treatment Options [Word Indexed] example: surgical resection.tp. up Update Code [Phrase Indexed] example: 9703.up.
Childhood Cancers Sentence Syntax: limit 1 to childhood cancers
Change to PDQ Cancer Information File from another database Command Syntax: ..c/pdqc Sentence Syntax: use pdqcSample PDQC Document
Accession Number PDQC-000006 Update Code 9703 Cancer Name Gastric cancer Synonyms Stomach cancer. Cell Type Stage, gastric cancer. Solid tumor. Adult solid tumor. Cellular diagnosis, gastric cancer. Mixed adenocarcinoma of the stomach. Diffuse adenocarcinoma of the stomach. Intestinal adenocarcinoma of the stomach. Gastrointestinal cancer. Adenocarcinoma of the stomach. Body system/site cancer. Stage 0 gastric cancer. Cancer. Recurrent gastric cancer. Stage IV gastric cancer. Stage III gastric cancer. Stage II gastric cancer. Stage I gastric cancer. Gastric cancer. Prognosis (A separate statement containing information on screening for gastric cancer is also available in PDQ.) Cancer of the distal half of the stomach has been decreasing in the United States since the 1930s. However, in the last 2 decades, the incidence of cancer of the cardia and gastroesophageal junction has been rapidly rising. The incidence of this cancer in patients especially under 40 years of age has increased dramatically. In localized distal gastric cancer, more than 50% of the patients are curable. However, early stage disease currently accounts for only 10%-20% of all cases diagnosed in the United States. The remaining patients present with metastatic disease in either regional or distant sites. The overall survival rate in these -sample truncated- Stage Information Stages are defined by TNM classification.[1] -- TNM definitions -- Primary tumor (T) Principal factor is degree of penetration of stomach wall by carcinoma TX: Primary tumor cannot be assessed T0: No evidence of primary tumor Tis: Carcinoma in situ: intraepithelial tumor without invasion of the lamina propria T1: Tumor invades lamina propria or submucosa T2: Tumor invades the muscularis propria or the subserosa* T3: Tumor penetrates the serosa (visceral peritoneum) without invading adjacent structures** T4: Tumor invades adjacent structures** *Note: A tumor may penetrate the muscularis propria with extension into the gastrocolic or gastrohepatic ligaments or into the greater or lesser omentum without perforation of the visceral peritoneum covering these structures. In this case, the tumor is classified T2. If there is gross or microscopic perforation of the visceral peritoneum covering the gastric ligaments or omenta, the tumor should be classified T3. **Note: The adjacent structures of the stomach are the spleen, transverse colon, liver, diaphragm, pancreas, abdominal wall, adrenal gland, kidney, small intestine, and retroperitoneum. Intramural extension to the duodenum or esophagus is classified by the depth of greatest invasion in any of these sites, including stomach. - sample truncated - Cellular Classification The cellular classification relates only to adenocarcinomas and not to other cell types such as lymphoma and sarcomas.[1] Adenocarcinomas can be divided into the following subtypes: fungating or polypoid ulcerating superficial spreading diffusely spreading (linitis plastica) Microscopically, four histologic types of adenocarcinoma may prove to have prognostic significance: intestinal pylorocardial (or antral) signet ring cell [2] -sample truncated- Treatment Overview The designations in PDQ that treatments are "standard" or "under clinical evaluation" are not to be used as a basis for reimbursement determinations.. Treatment Options Stage 0 gastric cancer Stage 0 is gastric cancer confined to mucosa. Experience in Japan where stage 0 is diagnosed frequently, indicates that greater than 90% of patients treated by gastrectomy with lymphadenectomy will survive beyond 5 years. An American series has confirmed these results.[1] References: 1. Green PH, O'Toole KM, Slonim D, et al.: Increasing incidence and excellent survival of patients with early gastric cancer: experience in a United States medical center. American Journal of Medicine 85(5): 658-661, 1988. Stage I gastric cancer Surgical resection including lymphadenectomy is the treatment of choice for stage I gastric cancer. If the lesion is not in the cardioesophageal junction and does not diffusely involve the stomach, subtotal gastrectomy is the procedure of choice since its use is associated with improved survival over other procedures. When the lesion involves the cardia, proximal subtotal gastrectomy or total gastrectomy (including a sufficient length of esophagus) may be performed with curative intent. If the lesion diffusely involves the stomach, total gastrectomy is required. At a minimum, surgical resection should include greater and lesser omentum and regional lymph nodes. Note that in patients with stage I gastric cancer perigastric lymph nodes may contain cancer. - sample document truncated-
Some material in the PDQ database is from copyrighted publications of the respective copyright claimants. Users of the database are referred to the publication data appearing in the bibliographic citations, as well as to the copyright notices appearing in the original publication, all of which are hereby incorporated by reference. The NCI represents that PDQ is formulated with a reasonable standard of care. Except for this representation, NCI makes no representations or warranties, express or implied, including any implied warranty of merchantability or fitness for a particular purpose, with respect to PDQ. The documents contained in PDQ may be retained for personal or educational use only. Information should not be edited or modified. Any resale or redistribution of all or portions of the information is not permitted.
Because use of the PDQ database for insurance reimbursement decisions is contrary to the nature of the database, which is designed as a research tool and not to reflect all possible treatment options, customers agree to not make the database available to users who wish to use it for reimbursement decision purposes.
Revised 7 July, 1998